When an amide is treated with bromine in an aqueous or ethanolic solution of sodium hydroxide, degradation of amide takes place leading to the formation of primary amine. This reaction involves the degradation of amide and is popularly known as Hoffmann bromamide degradation reaction. In the given molecule, amide part convert to amine with bromine in sodium hydroxide. Now, nucleophilic acyl substitution reaction takes place to get the final product as shown below.





