Better is the leaving group higher will be the reactivity of acyl compounds towards nucleophilic acyl substitution. Weaker is the base, better is the leaving group. Weaker bases are derived from stronger acids.
The relative reactivities of acyl compounds towards nucleophilic substitution are in the order of
NEET UG 2008 — Chemistry Organic Chemistry
2008mcqmedium
The relative reactivities of acyl compounds towards nucleophilic substitution are in the order of
Official previous-year question
Held on 30 Apr 2008 · Verified 9 Jul 2026.
Options
- A
Acyl chloride > Ester > Acid anhydride > Amide
- B
Acyl chloride > Acid anhydride > Ester > Amide
- C
Ester > Acyl chloride > Amide > Acid anhydride
- D
Acid anhydride > Amide > Ester > Acyl chloride
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