Key Idea Lesser the electron density of acyl carbon atom, more will be the susceptibility of nucleophile to attack it. The Cl atom has strong −I effect and weakest +R effect because of the weak π-bond between the small sized C-atom and large sized Cl atom. Thus, in CH3COCl, acyl carbon has least electron density and hence, more susceptible for nucleophilic attack.
Among the given compounds, the most susceptible to nucleophilic attack at the carbonyl group is
NEET UG 2010 — Chemistry Organic Chemistry
2010mcqmedium
Among the given compounds, the most susceptible to nucleophilic attack at the carbonyl group is
Official previous-year question
Held on 30 Apr 2010 · Verified 9 Jul 2026.
Options
- A
CH3COOCH3
- B
CH3CONH2
- C
CH3COOCOCH3
- D
CH3COCl
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