
Related Theory In the Clemmensen reduction, underlying substance must not react to the acidic conditions. The acid sensitive base substance reacts in the Wolff-Kishner reduction that has a strong base. The reaction is not for the substances that are sensitive to acids. Caution The Clemmensen reduction involves the conversion of ketone or aldehydes into alkanes whereas the Wolff Kishner reduction involves the conversion of carbonyl groups into methylene groups