Sickle cell anaemia is caused by the substitution of Glutamic acid by valine at the sixth position of the beta globin chain of the haemoglobin molecule. It is an example of point mutation. The substitution of amino acid in the globin protein results due to the single base substitution at the sixth codon of the beta globin gene from GAG to GUG. Thus, option (2) is correct
Select the correct statements about sickle cell anaemia. (A) There is a change in gene for beta globin. (B) In the beta globin, there is valine in…
NEET UG 2023 — Zoology Principles of Inheritance and Variation
2023mcqmedium
Select the correct statements about sickle cell anaemia. (A) There is a change in gene for beta globin. (B) In the beta globin, there is valine in the place of Lysine. (C) It is an example of point mutation. (D) In the normal gene U is replaced by A. Choose the correct answer from the options given below:
Official previous-year question
Held on 30 Apr 2023 · Verified 9 Jul 2026.
Options
- A
(A),(B) and (D) only
- B
(A) and (C) only
- C
(B), (C) and (D) only
- D
(B) and (D) only
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