Menopause is a senile change in ovaries. After menopause the level of pituitary gonadotropins remain same or slightly increase. FSH is more than LH; but the ovaries are not responding to these hormone, because all the ovarian follicles are converted into follicular atresia. There is decline in the level of progesterone and estrogen. Initially the blood inside the uterus clots, but it is liquefied by the enzyme plasmin released by uterus. Menstrual fluid which is discharged cannot clot again.