The chemical substances, which are used to kill or repel pest are called pesticides. The pesticides, which are used to destroy weeds are called herbicides. Herbicides are used in agriculture to control the weeds. They inhibit plant growth by blocking the biosynthesis of amino acids or photosynthetic activities of plants. Transgenic plants resistant to several herbicides, eg, glyphosate, gluphosinate, sulphonylireas etc, have been successfully developed. Main objective of production/use of herbicide resistant genetically modified crops is to reduce herbicide accumulation in food articles for health safety.