Cholecystokinin and secretin both hormones increase the secretion of pancreatic juice. Cholecystokinin (CCK), formerly called pancreozymin, a digestive hormone is released with secretin when food from the stomach reaches the first part of the small intestine. The release of enzymes from the pancreas, an action ascribed to pancreozymin; and the contraction of the gallbladder, which forces bile into the duodenum, an action ascribed to cholecystokinin. Secretin is a hormone that regulates water homeostasis and influences the environment of the duodenum by regulating secretions in the stomach, pancreas, and liver.