The word 'MATHEMATICS' consists of 11 letters including two M′s, two T′s and two A′s,
Now, first we will arrange letters _M_A_T_H_E_M_A_T_I_.
Here, we have 10 gaps to fill C&S.
The number of words with or without meaning can be formed from the word MATHEMATICS when C,S does not come together is
=2!⋅2!⋅2!9!×C210×2!
=2!⋅2!9×8×7×6!×210×9
=5670
Hence this is the correct option.