The correct option is (c).
Explanation
Goiter is a pathological condition characterized by the enlargement of the thyroid gland. It is primarily associated with nutritional deficiencies affecting the synthesis of thyroid hormones, which regulate metabolism, growth, and development.
Statement-wise Analysis:
- Statement 1 is Incorrect. Goiter is caused by a deficiency of Iodine in the diet, not Calcium. Iodine is a critical micronutrient required for the production of thyroid hormones (thyroxine and triiodothyronine). When iodine levels are low, the thyroid gland enlarges in an attempt to trap more iodine from the blood.
- Statement 2 is Correct. Iodine deficiency, particularly during pregnancy and early childhood, can lead to severe developmental disorders. In children, it can cause cretinism, a condition characterized by stunted physical growth and mental disability (low intelligence quotient).
- Statement 3 is Correct. The hallmark symptom of goiter is the swelling of the thyroid gland, which is located in the neck region. This manifests as a visible lump or enlargement in the neck.
Key Takeaway:
Goiter is an iodine-deficiency disorder resulting in the enlargement of the thyroid gland and can lead to mental disability in children if the deficiency occurs during developmental stages.