Correct Option
The correct option is 2 only
Explanation
The thyroid gland secretes hormones, primarily Thyroxine (T4) and Triiodothyronine (T3), which regulate the basal metabolic rate (BMR), growth, and development. Iodine is essential for the synthesis of these hormones. Disorders of the thyroid are classified into hypothyroidism (deficiency) and hyperthyroidism (excess).
Statement-wise Analysis
- Statement 1 is Incorrect: Iodine is required for the synthesis of thyroid hormones. A dietary deficiency of iodine results in low levels of T3 and T4. This stimulates the anterior pituitary to release increased amounts of Thyroid Stimulating Hormone (TSH). The constant stimulation causes the thyroid gland to enlarge, resulting in simple goitre.
- Statement 2 is Correct: Cretinism is a disorder caused by hypothyroidism (deficiency of thyroid hormone) during pregnancy or infancy. It leads to stunted physical growth and mental retardation. Deficiency of thyroid hormones in adults causes Myxedema, characterized by lethargy and tissue swelling, not Cretinism.
- Statement 3 is Incorrect: Thyroid hormones play a vital role in maintaining the physiology of the reproductive system. Deficiency of these hormones (hypothyroidism) leads to menstrual irregularities (such as oligomenorrhea or menorrhagia), rather than ensuring regular cycles.
Key Takeaway: Iodine deficiency causes Goitre. Hypothyroidism leads to Cretinism in children and Myxedema in adults, and it disrupts menstrual regularity in females.