Correct Option
The correct option is 2 and 3 only.
Explanation
Insulin is a peptide hormone secreted by the pancreas. It plays a central role in the regulation of carbohydrate and fat metabolism in the body by controlling blood glucose levels.
Statement-wise Analysis
- Statement 1 is Incorrect: Insulin is not produced by the liver. It is produced by the beta cells of the Islets of Langerhans located in the pancreas. The liver is a target organ for insulin, where it promotes the storage of glucose as glycogen.
- Statement 2 is Correct: Insulin regulates blood sugar levels by facilitating the uptake of glucose into cells (muscle and adipose tissue) and inhibiting the production of glucose by the liver. This process lowers blood glucose concentration.
- Statement 3 is Correct: A deficiency in insulin production or the inability of cells to respond to insulin leads to a condition known as Diabetes Mellitus. This results in hyperglycemia (harmful elevation of blood sugar), which can cause long-term damage to various organs.
Key Takeaway
Insulin is secreted by the pancreas (beta cells) and lowers blood glucose levels. Its deficiency leads to Diabetes Mellitus. Conversely, Glucagon (alpha cells) raises blood glucose levels.