Option 1 -> "Conflict" means to be in disagreement or opposition, which is the opposite of "accord" (agreement/harmony).
Option 2 -> "Manage" means to handle or control something, unrelated to the meaning of accord.
Option 3 -> "React" means to respond to something, which doesn't oppose the concept of agreement.
Option 4 -> "Approve" means to accept or agree with something, which is similar to accord, not opposite.
Hence, Option 1: conflict -> "Accord" means to agree with or be in harmony with, while "conflict" means to disagree or be in opposition -> correct