Option 1 -> Salubrious means healthy or health-giving, which is an antonym.
Option 2 -> Wholesome means conducive to well-being or moral health, which is an antonym.
Option 3 -> Deleterious means harmful or damaging, which is a synonym.
Option 4 -> Advantageous means beneficial or favorable, which is an antonym.
Hence, Option 3: Deleterious -> Both "pernicious" and "deleterious" describe something that causes harm or damage, often in a subtle or gradual way. The other options all represent positive, beneficial qualities, making them antonyms rather than synonyms -> correct