Option 1 (Guilty) -> This is a synonym of culpable, meaning deserving blame or having committed an offense.
Option 2 (Responsible) -> This is similar to culpable in meaning, indicating accountability for wrongdoing.
Option 3 (Blameworthy) -> This is also a synonym of culpable, meaning deserving censure or blame.
Option 4 (Innocent) -> This is the opposite of culpable, meaning free from guilt or blame.
Hence, Option 4 (Innocent) -> Culpable means "deserving blame or guilty of wrongdoing," so its antonym is innocent, which means "not guilty or free from blame" -> correct